Clonal chromosome abnormalities in 54 cases of ovarian carcinoma
نویسندگان
چکیده
منابع مشابه
Clonal chromosome abnormalities in 54 cases of ovarian carcinoma.
As a prelude to assessing the relationship of chromosome alterations to clinical outcome in ovarian carcinoma, we report on the cytogenetic analysis on short-term cultures from 54 patients. All patients had histopathologically confirmed malignancy, with the majority of cases demonstrating serous ovarian adenocarcinomas. Structural alterations were evident in 52 cases, whereas numeric changes we...
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We present 2 cases of likely rare event. In case 1, 3rd degree consanguineous marriage revealed inv(6) with same break points in parents who were found to be phenotypically normal. The same inv(6) being inherited in progeny but presented with low AMH (anti Mullerian hormone) and high level of FSH (follicular stimulating hormone) leading to polycystic ovarian syndrome/premature ovarian failure. ...
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Distant metastases are rare during the course of ovarian carcinoma. Ovarian epithelial adenocarcinomas rarely metastasize to the skin which is seen in less than 4% of patients. It usually presents as subcutaneous nodules and, less commonly, as inflammatory metastases which mimic cellulitis or viral or bacterial skin infections. The histology in most of the tumours is grade 1 or 2 serous p...
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ژورنال
عنوان ژورنال: Cancer Genetics and Cytogenetics
سال: 1994
ISSN: 0165-4608
DOI: 10.1016/0165-4608(94)90179-1